Exoskeleton Treatment of Deconditioning Due to Limited Ambulation Caused by Illness or Injury

Exclusion Criteria

• •1. Currently involved in another intervention study.
• •2. Transferred to the intensive care unit or isolation-room stay.
• •3. Currently on a ventilator or extracorporeal membrane oxygenation (ECMO) machine.
• •4. Currently have a ventricular assist device (VAD) or an automatic implantable cardioverter-defibrillator (AICD).
• •5. Advanced heart failure - ejection fraction of \< 20%.
• •6. Documented cardiovascular risk from exercise.
• •7. Resting heart rate \<50 bpm or \>120 bpm.
• •8. Uncontrolled or new (within 24 hours) arrythmias.
• •9. Resting blood pressure below 90/70 or above 160/100.
• •10. Oxygen saturation (O2 sat) \< 90% during rest.
• •11. Uncontrolled or severe orthostatic hypotension that limits standing tolerance.
• •12. Cardiac ischemia within 24 hours.
• •13. Unresolved or new (within 24 hours) deep vein thrombosis.
• •14. Concurrent severe neurological pathology/disease or stroke within 72 hours.
• •15. Open skin ulcerations on any body surfaces in contact with exoskeleton.
• •16. Acute fracture
• •17. Osteoporosis
• •18. Active heterotrophic ossification (HO) of the lower extremity, hip dysplasia, or hip/knee axis abnormalities.
• •19. Current chemotherapy
• •20. Inability to speak or understand the English language.
• •21. Inability to cooperate in tests/exercises.
• •22. Hip flexion contracture greater than \~17°.
• •23. Knee flexion contracture greater than 12°.
• •24. Unable to achieve neutral ankle dorsiflexion with passive stretch (neutral with max 12° knee flexion).
• •25. Cognitive impairments - unable to follow 2 step commands or to communicate pain or to stop session.
• •26. Pregnancy
• •27. Any reason the physician may deem as harmful to the participant to enroll or continue in the study.