Stereotactic Ablative Radiotherapy for Refractory Ventricular Tachycardia

Inclusion Criteria

• •Documented sustained ventricular arrhythmias refractory to or not a suitable candidate for catheter based RFA ablative therapy
• •Documented sustained ventricular arrhythmias refractory to or not a suitable candidate for cardiac sympathetic denervation therapy
• •Documented ventricular arrhythmias refractory to or not a suitable candidate for cardiac transplantation
• •Documented sustained ventricular arrhythmias refractory to or not a suitable candidate for additional medical management
• •ICD in place with documented episodes recurrent VT despite best clinical management previous refusal of ICD with recurrent sustained ventricular arrhythmias
• •If ischemic cardiomyopathy, myocardial infarction occurred more than one month prior to enrollment
• •No history of prior radiotherapy to the chest
• •Prescribed dose must be deliverable using SABR technique
• •Age ≥ 18 years
• •Karnofsky Performance Status (KPS) \> 70
• •If a woman is of childbearing potential, a negative serum pregnancy test must be documented. Women of childbearing potential must agree to use adequate contraception (hormonal or barrier method of birth control; or abstinence) for at least 4 weeks after study treatment.
• •Ability to understand and willingness to sign a written informed consent