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Utility of High Flow Nasal Cannula in CO Toxicity | Clinical Trials | Clareo Health

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COMPLETEDNANCT03342209

Utility of High Flow Nasal Cannula in CO Toxicity

determination of the half-life of COHb in CO-poisoned patients with high flow nasal oxygen therapy in the ED.

Lead sponsor: Kocaeli University•1 locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Kocaeli University

Carbon monoxide (CO) poisoning is common and potentially fatal environmental emergency which requires immediate attention. It is responsible for up to 40,000 emergency department (ED) visits and 5000 to 6000 deaths per year, making it one of the leading causes of poisoning death in the United States. The management options for CO poisoning are limited to high flow oxygen by face mask or hyperbaric oxygen treatment. While half-life of carboxyhemoglobin (COHb) in a patient treating with high flow oxygen via a nonbreathing face mask is 90 minutes, it becomes 30 minutes with hyperbaric oxygen treatment (HBO). The hypothesis of this study is using high flow nasal oxygen therapy in the CO poisoning may be more effective and safer treatment method comparing to standard oxygen therapy in the ED. Also, it may be a safe promising alternative of hyperbaric oxygen therapy. The aim of the study is to determine the half-life of COHb in CO-poisoned patients with high flow nasal oxygen therapy in the ED.

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•The patients who are admitted to the emergency department with CO poisoning with a CoHB level of \>10%.
•The patients who accept to participate in the study.

Exclusion Criteria

•The patients who are \<18 years old.
•The patients who need mechanical ventilation
•The patients who are implemented oxygen more than 30 minutes before the ED admission
•The patients who will be transferred to the hyperbaric oxygen center before the CoHB levels are decreased to the half.

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: April 10, 2018Terms

Trial snapshot

StatusCOMPLETED

PhaseNA

Enrollment35

Start dateMar 2017

Last updatedApr 10, 2018

Condition

Carbon Monoxide Poisoning Environmental Exposure

Locations shown

Kocaeli University Medical Faculty

Kocaeli, Izmit

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: April 10, 2018Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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