Study of VTD in Waldenstrom's Macroglobulinemia

Inclusion Criteria

• •Age of 19 or older
• •Newly diagnosed Waldenstrom's macroglobulinemia or lymphoplasmacytic lymphoma
• •Previously untreated with chemotherapy
• •ECOG performance status of 2 or lesser
• •Peripheral blood white blood cell count ≥ 3,500/uL
• •Peripheral blood neutrophil count ≥ 1,000/uL
• •Peripheral blood platelet count ≥ 20,000/uL
• •Peripheral blood hemoglobin ≥ 6.0g/dL
• •Serum total bilirubin ≤ 2.0 mg/dL
• •Serum aspartate aminotransferase ≤ 2.5 x (upper normal limit)
• •Serum alanine aminotransferase ≤ 2.5 x (upper normal limit)