Stop or Ongoing Oral Anticoagulation in Patients Undergoing Pvp (SOAP)

Exclusion Criteria

• •History of prostate cancer
• •Previous pelvic radiotherapy
• •History of stenosis of the urethra
• •Patient with one or more bladder polyps
• •Patient under antiplatelet agent other than aspirin
• •Allergy to heparin or history of heparin-induced thrombocytopenia
• •Patients under anticoagulant injectable therapy at baseline (heparin, LMWH (Low Molecular Weight Heparin), fondaparinux)
• •Any mechanical prosthetic heart valve
• •Stroke (ischemic or hemorrhagic), systemic embolism or transient ischemic attack within past 12 weeks
• •Venous thromboembolism (deep vein thrombosis and/or pulmonary embolism) within past 12 weeks
• •Major bleeding within past 6 weeks
• •Severe renal insufficiency (calculated creatinine clearance \< 30 mL / min)
• •Thrombocytopenia (platelet count \< 100 x 10\^9 / L)
• •Life expectancy \< 1 month
• •Condition that impairs compliance with trial protocol (e.g. cognitive impairment, uncontrolled psychiatric condition, geographic inaccessibility)
• •Contra-indication to PVP surgery or contra-indication to general anesthesia
• •Protected patients : majors under some form of guardianship
• •Patient participating in another clinical study