Clinical Characteristics, Treatment and Prognosis of Chest Tightness Variant Asthma

Inclusion Criteria

• •1. all subjects agreed to participate, understand the project, observe the use of drugs, agree to follow-up, and signed informed consent;
• •2. the age of more than 14 and less 80 years old, gender and ethnicity are not limited;
• •3. the duration time was more than 6 months,and chest tightness was the only complaint, without breathing, short of breath, chronic cough;
• •4. no wheezing;
• •5. a diagnosis of asthma supported by one or more other characteristics:
• •* bronchial provocation test positive;
• •* improvement in forced expiratory volume at one second (FEV1) of more than 12% and 200 mL after inhaled salbutamol;
• •* variability in diurnal peak expiratory flow (PEF) of more than 10% for one day during one week.
• •6. bronchodilator and glucocorticoid treatment is effective;
• •7. exclude the following diseases by the corresponding doctors: coronary heart disease, myocarditis, heart failure, GERD, neuromuscular disease, and mental disease.