Protection During Cardiac Surgery.

Exclusion Criteria

• •Emergency surgery
• •Redo surgery
• •Patient treated with Nicorandil, repaglinid or sulfonylurea 48 hours prior to surgery
• •Low cardiac output requiring catecholamine infusion or circulatory assistance prior to surgery
• •Severe renal failure: dialysis or glomerular filtration rate \< 30 mL/min
• •Severe liver failure (spontaneous INR \>2)
• •Severe respiratory insufficiency (VEMS \<40% of predicted value)
• •Contra-indication to sevoflurane and propofol
• •Myocardial infarction \< 7 days
• •Severe upper limb arterial disease
• •Heparin-induced thrombopenia
• •Active infection under antibiotic treatment
• •Any other surgery combined with the aortic valve surgery: myotomia of Morrow (hypertrophic myocardiopathy), treatment of heart rhythm disorder, inter-atrial communication closure, mitral valve replacement, tricuspid valve replacement, pulmonary valve replacement.
• •Pregnant women
• •Currently participating in another trial which may interfere with ProCCard results
• •Not benefiting from a social insurance or similar system
• •Patient under legal protection