Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
NYU Langone Health
1. To test the feasibility of wearing an earphone system delivering acoustic stimulation during a night of sleep in adult epilepsy patients monitored in an inpatient unit.
2. To determine the acute physiological effects of low-frequency acoustic stimulation on interictal epileptiform discharge (IED) frequency during NREM sleep in adult patients with epilepsy in an ambulatory setting.
3. To determine the feasibility of applying low-frequency acoustic stimulation in a long-term home setting in adult epilepsy patients with frequent nocturnal seizures.
Age
18–60
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
18-60 years old
Able to provide informed consent
MOCA ≥26
Fluent in English
Frequent nocturnal IEDs (≥ 10% of the sleep record)
Frequent nocturnal seizures (≥1 per week)
You may not be if
Hearing impairment
Diagnosis of a sleep disorder (sleep apnea, periodic limb movements of sleep, or other medical conditions with frequent arousals)
Psychoactive medication use (other than AEDs, for example SSRIs, antipsychotics, BDZ, or stimulants)
Seizures ≤ 24 hours prior to study.
Alcohol or recreational drug use in the 24 hours prior to the study
BMI ≥ 30
MOCA \<26
History of recent travel across time zones within the 1 month prior to study activities
No medication changes at least 1 month before study, and during 3 months of study activities
