Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University Hospital, Montpellier
With
Centre National de la Recherche Scientifique, France
B cells will be collected during procedures planned for patients' standard care. Peritoneal fluid and peripheral blood of patients will be collected during coelioscopy for exploration of ovarian cysts or dialysis for treatment of chronic renal insufficiency.
Regulatory B cells (Breg cells) will be measured in peritoneal fluid and in peripheral blood after in vitro stimulation and assessment of intracellular interleukin-10 by flow cytometry. Proportion of Breg cells among B cells will be compared between peritoneal fluid and peripheral blood in both groups.
Different protocols to induce differentiation of B cells into Breg cells will be tested and compared.
Age
18–80
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
woman over 18 year old undergoing exploration of ovarian cysts by coelioscopy
patient with chronic renal insufficiency undergoing peritoneal dialysis
informed consent obtained
You may not be if
pregnancy or breast-feeding
non affiliation to health care insurance
treatment with corticosteroids over 15 mg/day
treatment with rituximab
Clareo Health | Anti-inflammatory Cells in Peritoneal Cavity