VOLtage-based Contrast Media AdaptatioN in Coronary Computed Tomography Angiography

Exclusion Criteria

• •1. Subject is a pregnant or nursing female. Exclude the possibility of pregnancy:
• •* By testing (serum or urine beta HCG) within 24 hours before study agent administration, or
• •* By surgical sterilization, or
• •* Post-menopausal, with minimum one (1) year history without menses.
• •2. Subject is chosen by the automated tube voltage selection algorithm (or adjusted by the technologist) to be scanned using a tube voltage that is not 70, 80, 90, 100, 110, 120, or 130 kV.
• •3. Subject is chosen by the automated tube voltage selection algorithm (or adjusted by the technologist) to be scanned using a tube voltage that has previously reached the maximum subject number (20 subjects per tube voltage).
• •4. Subject has an acute psychiatric disorder.
• •5. Subject is unwilling to comply with the requirements of the protocol.
• •6. Subject has previously entered this study.
• •7. Subject has an allergy against iodinated contrast agents or pharmaceutical stressors used in this study.
• •8. Subject has impaired renal function (creatinine \> 1.5 mg/dl).
• •9. Subject is in unstable condition.