Lead Sponsor

University of Zurich

Collaborators

National Center of Cardiology and Internal Medicine named after academician M.Mirrakhimov

Age

16 - No limit years

Sex

ALL

Healthy Volunteers

No

•high altitude pulmonary hypertension confirmed by clinical presentation and mean pulmonary artery pressure \>30 mmHg measured by echocardiography at altitude of residence.
•healthy subjects (high altitude controls)
•Both genders
•Age \>16 y
•Kyrgyz ethnicity
•born, raised and currently living at \>2500 m
•healthy subjects currently living at \<1000 m (low altitude controls)

•Pulmonary hypertension from other causes, in particular from left ventricular failure as judged clinically and by echocardiography
•Excessive erythrocytosis
•Other coexistent disorders that may interfere with the cardio-respiratory system and sleep
•Regular use of medication that affects control of breathing
•Heavy smoking