Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
NYU Langone Health
Age
18–30
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Patients:
current DSM-5-defined diagnosis of a schizophrenia or bipolar disorder. A best estimate diagnostic approach will be utilized in which information from the Diagnostic Interview for Genetic Studies (DIGS) is supplemented by information from family informants, psychiatrists, and medical records to generate a diagnosis as needed
no alcohol or substance abuse during the last 6 month
no current substance-induced psychotic disorder or a psychotic disorder due to a general medical condition determined by DSM-5 criteria
ages 18 to 30 years old;
any race
competent and willing to sign informed consent
within 5 years from the disease onset.
Siblings:
have the same biological parents as their PSD sibling
any race
no current or past history of psychotropic medication usage
no alcohol or substance abuse during the last 6 months
competent and willing to sign informed consent;
ages 18 to 30 years old.
Healthy controls:
matched for age to PSD patients
no current or past history of psychotropic medication usage
no prodromal symptoms and no family history of PSD
no alcohol or substance abuse during the last 6 months
competent and willing to sign informed consent.
all attempts will be made to recruit controls with similar parental SES as patients. However, given that PSD are both a neurodevelopmental and familial disorder, exact matching for educational level or IQ may neither be possible nor desirable.
have the same biological parents as their PSD sibling
any race
no current or past history of psychotropic medication usage
no alcohol or substance abuse during the last 6 months
competent and willing to sign informed consent;
ages 18 to 30 years old.
You may not be if
a serious neurological or endocrine disorder or any medical condition or treatment known to affect the brain, 2) organic brain disorder, mental retardation, or significant medical illness;
significant risk of suicidal or homicidal behavior;
must not have met DSM-5 criteria for current alcohol or drug dependence in the last 6 months;
contraindications to MRI scanning (i.e., metal implants, pacemakers, pregnancy, etc.);
documented loss of consciousness (LOC) for longer than 30 minutes or LOC with any neurological sequelae.
