TRanslesIonal Assessment of Gradients During Endovascular Therapy

Inclusion Criteria

• •Inclusions:
• •Age \>18 y/o, undergoing clinically indicated endovascular therapy (balloon angioplasty, stenting, atherectomy or combination) for lower extremity peripheral artery disease (PAD) and claudication or critical limb ischemia (CLI). Rutherford Category 2-6.
• •Includes iliac lesions, common femoral, superficial femoral artery, popliteal artery and tibial vessels
• •A subject can be enrolled more than once (up to a maximum of two total times) for treatment of a staged lesion but must wait at least 6 weeks from the completion of the last study enrollment.
• •Exclusions:
• •No pregnant females
• •No vulnerable populations (dementia, prisoners, children)
• •Baseline bradycardia (heart rate \<50 beats/min) or hypotension (systolic blood pressure \<90 mm Hg) will be excluded from receiving adenosine