Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Ad scientiam
Age
18–60
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
MS patients:
subjects: 18 Years to 60 Years
with a confirmed and documented MS diagnosis, per the 2010 Revised McDonald criteria
with or without MS maintenance and/or symptomatic treatment, if MS maintenance and/or symptomatic treatment: stable for the past 6 months before enrolment (Centrally acting antalgics, antidepressant or neuroleptic treatment are authorized but shall not be modified in the past 2 months before enrolment)
with an EDSS \[0;7\] in the past 6 months before enrolment
with an EDSS \[0;7\] in the past 6 months before enrolment
with no evidence of EDSS score change since the last measure available
with no evidence of relapse in the past 6 months before enrolment
enrolled in or benefiting of a Social Security program
who have read the information sheet and signed the informed consent form
Healthy volunteers:
subjects: 18 Years to 60 Years
with no evidence of walk limitation (as per clinician's judgment) nor walking aid
no personal and familial history of inflammatory disease (e.g. rheumatoid arthritis) or multiple sclerosis
matched to the sociodemographic characteristics of MS patients sample (age, sex, height, weight, education)
enrolled in or benefiting of a Social Security program
who have read the information sheet and signed the informed consent form
MS patients and Healthy volunteers:
Participants wearing pacemakers, implantable defibrillators, or hearing aids
Inability to use their right hand for the Coordination test (MCT)
Evidence of neurologic or psychiatric disorder other than MS, including but not limited to major head trauma, seizures or systemic medical diseases that are likely to affect cognitive functioning
Evolutive rheumatology disease
Any vision (ex. short-sightedness (-6; +6); congenital dyschromatopsia and glaucoma) or hearing conditions that could influence the performing of the tests
Omission of the usual visual and/or walking aids if it's usually needed
Acute asthenia (score\>7 on a visual analogic scale)
Systemic corticosteroid treatment in the past 30 days before enrolment
Intramuscular botulinic toxin injection in the past 4 months before enrolment
Change in centrally acting antalgic, antidepressant or neuroleptic treatment in the past 2 months before enrolment
Rehabilitation in the past 6 months before enrolment
Pregnant and nursing women - Person under guardianship or curatorship
Bedridden patients or patients with a daily activity of less than 2 hours per day
Inability to use a mobile application
Current drugs or/and alcohol abuse that could influence performance on the tests (clinician's judgment)
Participation to another study Healthy volunteers who will not match the sociodemographic characteristics of MS patients will not be included in the study.
You may not be if
Patient experiencing a relapse once enrolled in the study
Patient with a maintenance and symptomatic MS treatment modification
Use of centrally acting antalgics, antidepressant or neuroleptic once enrolled in the study
Substance or/and alcohol abuse that could influence performance on the tests between inclusion and follow-up visits (clinician's judgement)
Omission or change in the usual visual and/or walking aids
Acute asthenia (score\>7 on a visual analogic scale) at the follow-up visit.
Clareo Health | Digitalization of Neurofunctional Tests Via a Mobile Application DAMS for Multiple Sclerosis Patients
