Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Guangdong Provincial People's Hospital
Age
18–any
Sex
FEMALE
Healthy volunteers
Not accepted
You may be eligible if
Histologically or cytologically confirmed HER2 positive invasive breast carcinoma
Clinical stage Ⅱ-ⅢC
Eastern Cooperative Oncology Group(ECOG) performance status 0 to 1 within 14 days of study entry
Normal (greater than 50%) left ventricular ejection fraction (LVEF) by echocardiography
Signed informed consent
Adequate organ function within 2 weeks of study entry:
Absolute neutrophil count \>1500/mm3, Hgb \>9.0 g/dl and platelet count \>100,000/mm3 Total bilirubin \< upper limit of normal Creatinine \< 1.5 mg/dL or calculated cranial cruciate ligament (CrCL) \>50mL/min using the Cockcroft Gault equation serum glutamate oxaloacetate transaminase(SGOT)(AST) or serum glutamic oxaloacetic transaminase(SGPT)(ALT) and Alkaline Phosphatase must be within the range allowing for eligibility
Patients must be over 18 years old.
Women of childbearing potential must have a negative serum pregnancy test performed within 7 days prior to the start of treatment
Women of childbearing potential and men must agree to use adequate contraception (barrier method of birth control) prior to study entry and for the duration of study participation.
History of previous or current malignancy at other sites with the exception of adequately treated carcinoma in-situ of the cervix or basal or squamous cell carcinoma of the skin. Patients with a history of other malignancies, who remain disease free for greater than five years are eligible.
You may not be if
Metastatic disease
Clareo Health | TCH Versus EC-TH as Neoadjuvant Treatment for HER2-Positive Breast Cancer
