Prospective, Single-Center, Non-Randomized Study of the PhysioWave™ Cardiovascular Analyzer

Exclusion Criteria

• •Known significant carotid or femoral artery stenosis
• •Non-palpable (non-detectable) arterial pulse at the sites of measurements
• •Pacemaker, defibrillator, or other cardiac stimulator
• •Erratic, accelerated or mechanically controlled irregular heart rhythm, or an arrhythmia
• •History of cardiac valve disorder or cardiac valve disease
• •History of venous disease, including venous insufficiency or deep vein thrombosis
• •History of peripheral artery disease
• •Requirement for supplemental oxygen
• •Neuromuscular disorders that cause shaking or tremors (such as Parkinson's disease or Multiple Sclerosis), or other disease or condition affecting balance
• •Amputation or malformation of any limb or extremity (foot, leg, or arm) which would impede the placement of blood pressure cuffs or standing on the scale with two feet.
• •Known or suspected pregnancy
• •Inability to provide informed consent
• •Mental incompetence or a prisoner status
• •Current participation in a clinical trial of another investigational drug or device in which the study endpoint has not been met
• •BMI \> 40
• •Subjects \> 400 lbs
• •Subjects on strong vasoactive drugs, such as those used to control high blood pressure, for \<30 days
• •Blood loss or blood donation of ˃ 550 mL within 30 days before study procedure