Waterjet Ablation Therapy for Endoscopic Resection of Prostate Tissue II

Exclusion Criteria

• •BMI ≥ 42.
• •Patients unable to stop anticoagulants, antiplatelet agents, or non-steroidal anti-inflammatory agents (NSAIDs, including aspirin greater or equal to 100mg) prior to treatment per standard of care.
• •Participants using systemic immune-suppressants including corticosteroids (except inhalants); unable to withhold non-steroidal anti-inflammatory agents (NSAIDs, including aspirin) prior to treatment per standard or care except for low dose aspirin (e.g. less than or equal to 100mg).
• •Contraindication to both general and spinal anesthesia.
• •Any severe illness that would prevent complete study participation or confound study results.
• •History of prostate cancer or current/suspected bladder cancer. Prostate cancer should be ruled out before participation to the satisfaction of the investigator if PSA is above acceptable thresholds.
• •History of actively treated bladder cancer within the past two (2) years.
• •Clinically significant bladder calculus or bladder diverticulum (e.g., pouch size \>20% of full bladder size).
• •Active infection, including urinary tract infection or prostatitis.
• •Urinary catheter use daily for 90 or more days consecutively.
• •Previous urinary tract surgery such as e.g. urinary diversion, artificial urinary sphincter or penile prosthesis.
• •Ever been diagnosed with a clinically significant urethral stricture or meatal stenosis, or bladder neck contracture.
• •Known damage to external urinary sphincter.
• •Has had an open heart surgery, or cardiac arrest \< 180 days prior to the date of informed consent.
• •Participants using anticholinergics specifically for bladder problems. Use of medications with anticholinergic properties is allowable provided the patient does not have documented adverse urinary side effects from these medications.
• •Subject is unwilling to accept a transfusion should one be required.