Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Centre Hospitalier Universitaire de Besancon
Age
18–76
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Performance status ECOG-WHO 0 or 1
Histologically proved metastatic colorectal adenocarcinoma, with non-resectable metastases
Adequate hematological, hepatic, and renal functions
Signed written informed consent
You may not be if
Previous treatment (chemotherapy, targeted therapy, surgery) for metastatic disease
History of autoimmune disease
Acute infectious disease
Known hypersensitivity grade 3-4 or contraindication to any of the study drugs
Patient with any medical or psychiatric condition or disease which would make the patient inappropriate for entry into this study.
Bevacizumab contraindication
Brain metastases
Other malignancy within the last 2 years, except for adequately treated carcinoma in situ of the cervix or squamous carcinoma of the skin, or adequately controlled limited basal cell skin cancer.
Pregnancy, breast-feeding or absence of adequate contraception for fertile patients
Patient under guardianship, curator or under the protection of justice.
