Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Murdoch Childrens Research Institute
With
Sydney Children's Hospitals Network
Baylor College of Medicine
Boston Children's Hospital
The Cleveland Clinic
University of Texas, Southwestern Medical Center at Dallas
Royal Children's Hospital
Children's Hospital of Philadelphia
Queensland Children's Hospital
Perth Children's Hospital
Women and Children's Hospital
Istituto Giannina Gaslini
Flinders Medical Centre
Age
0–2
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Younger than 2 years (chronological age)
Scheduled for anaesthesia that is expected to last at least 2 hours (and/or total operating room time is scheduled to be at least 2.5 hours)
Has a legally acceptable representative capable of understanding the informed consent document and providing consent on the participant's behalf.
You may not be if
Known neurologic, chromosomal or congenital anomaly which is likely to be associated with poor neurobehavioural outcome
Existing diagnosis of behavioural or neurodevelopmental disability
Prematurity (defined as \< 36 weeks gestational age at birth)
Birth weight less than 2 kg.
Congenital cardiac disease requiring surgery
Intracranial neurosurgery and intracranial craniofacial surgery (isolated cleft lip is not an exclusion)
Previous cumulative exposure to general anaesthesia exceeding 2 hours
Planned future cumulative exposure to anaesthesia exceeding 2 hours before the age of 3 years.
Any specific contra-indication to any aspect of the protocol
Previous adverse reaction to any anaesthetic
Circumstances likely to make long term follow-up impossible
Living in a household where the primary language spoken at home is not a language in which we can administer the Wechsler Preschool and Primary School Intelligence Scale
Planned postoperative sedation with any agent except opioids (e.g. benzodiazepines, dexmedetomidine, ketamine, barbiturates, propofol, clonidine, chloral hydrate, and other non-opioid sedatives). For example if such sedation is planned for post-operative ventilation
Clareo Health | A Study to Compare the Long-term Outcomes After Two Different Anaesthetics
