This is a prospective randomized study to test the effects of thiazide and furosemide in bone parameters, which will be assessed by peripheral micro-tomography at baseline and 12 months later. The role of calciuria in these possible changes will be tested.
Age
18–80
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Estimated Glomerular Filtration Rate (calculated by CKD-EPI) between 30 and 60 ml/min
You may not be if
Diabetes;
chronic use of: steroid, bisphosphonates and calcium carbonate
