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Keep this study
Lead
Dr. Daniel P Morin, MD MPH FHRS
This study aims to determine whether stimulating earlier activation of the failing right ventricle in pulmonary hypertension reduces the effects of interventricular dependence in human subjects, thereby improving overall cardiac function and symptoms in patients with pulmonary hypertension and right ventricle failure with NYHA Class 3-4 symptoms.
Age
18–75
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Pulmonary hypertension, defined as pulmonary artery systolic pressure greater than 40 mm Hg by transthoracic echocardiogram or right heart catheterization
LVEF ≥ 50%
Baseline 6MWT distant \<400 meters
Baseline NYHA Functional class ≥ III
You may not be if
LVEF \< 50%
6MWT duration \> 400 meters
NYHA Functional class \< III
Left bundle branch block
Non-sinus rhythm
Severe aortic stenosis (Aortic valve area \< 1 cm2)
Severe mitral regurgitation
Acute cardiac failure
Dependency on intravenous inotropies
Severe obstructive pulmonary disease
Hypertrophic obstructive cardiomyopathy
Amyloidosis
Dependence on pacing
Clareo Health | Cardiac Resynchronization Therapy in Pulmonary Hypertension
