Effects of Prenatal Tobacco Smoke Exposure on Lung Function and Respiratory Epithelium Functionality in Newborns

Exclusion Criteria

• •prematurity \< 35GW
• •gemellary pregnancy
• •Birth weight \< 2200 g
• •neonatal respiratory distress syndrome (nasal oxygenotherapy \> 24 hours, invasive or noninvasive ventilation)
• •neonatal malformation with conséquences on lung function
• •neonatal liver or renal failure
• •high risk of heritable lung disease
• •contra-indication to saccharose or paracetamol antalgic use
• •language barrier,
• •mother refusal to declare or precise her tobacco consumption
• •no social security cover
• •informed consent form not signed