Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Seoul National University Bundang Hospital
With
Daiichi Sankyo Korea Co., Ltd.
* Elevated blood pressure is an established risk factor for recurrent stroke and vascular events in ischemic stroke survivors, but
* Current guideline (JNC VIII) has omitted or only partially covered a number of practical and important issues as follow;
* When and how we measure blood pressure?
* Is it justifiable to apply the same blood pressure threshold for office BP and home BP?
* Should stroke survivors be treated by the same BP goal for non-stroke subjects?
* Is it justifiable to apply the universal BP threshold for different mechanisms of ischemic stroke?
* Is it really about only blood pressure or might it really be "beyond blood pressure?"
* Lifestyle modification should accompany all the pharmacological intervention but is usually in adequate to initiate behavioral changes.
* Frequent BP measurement at home will provide more detailed and reliable information than occasional office BP's.
Age
19–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Ischemic stroke survivors within 7 days after onset
≥19 year-old male or female
Medically and neurologically stabilized enough to take BP-lowering medication
Mean systolic blood pressure ≥135 mm Hg during two days between at least 24 hours after onset and randomization (whether BP-lowering medication was prescribed or not)
Capable of taking oral medication
Capable of operating a wireless Bluetooth-equipped sphygmomanometer system and being expected to follow required procedures of the clinical trial
Patients who provided written informed consent
You may not be if
Pregnant, puerperium ≤30 days or on breastfeeding
enrolled in other interventional clinical trial
Being transferred to rehabilitation center or institutionalized
Being expected to have cerebral artery interventions within 3 months after randomization
Known allergic reactions to olmesartan, amlodipine or hydrochlorothiazide
Known severe hepatic disease
Advanced kidney dysfunction requiring dialysis
Being unlikely, in the opinion of the investigator, to comply with the clinical trial protocol or being unsuitable for any other reason.
Clareo Health | Optimization of Blood Pressure Management After Acute Ischemic Stroke and Its Prognostic Significance