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UNKNOWNNANCT03018483

Mechanical Ventilation- Weaning and Thoracic Impedance Tomography

The aim of this multicenter, randomized controlled trial is to evaluate the weaning time from mechanical ventilation comparing non-variable PSV, variable PSV, and Smart CareTM. This study is a multic...

Lead sponsor: Federico II University•1 locations•View source on ClinicalTrials.gov

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Contacts

Maria Vargas

CONTACT

+39 3396876440 [email protected]

Sponsors

Lead Sponsor

Federico II University

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•age≥18 years
•duration of controlled mechanical ventilation≥ 24 h
•temperature≤ 39°C
•hemoglobin≥ 6 g/dl
•ratio of arterial partial pressure of oxygen to inspiratory oxygen fraction - PaO2/FiO2≥150mmHg with positive end-expiratory pressure (PEEP)≤ 16 cmH2O
•ability of the patient to breathe spontaneously
•informed consent

Exclusion Criteria

•patient participated in another interventional trial within the last four weeks before enrollment
•peripheral neurological disease associated with impairment of the respiratory pump
•muscular disease associated with impairment of the respiratory pump
•unstable thorax with paradoxical chest wall movement
•planned surgery under general anesthesia within 72 hours
•difficult airway or intubation
•existing tracheotomy at ICU admission
•expected survival\<72 hours
•home mechanical ventilation or on chronic oxygen therapy
•suspected or confirmed pregnancy

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: December 11, 2019Terms

Trial snapshot

StatusUNKNOWN

PhaseNA

Enrollment342

Start dateMay 2017

Last updatedDec 11, 2019

Condition

Weaning From Mechanical Ventilation

Locations shown

University of Naples

Naples

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: December 11, 2019Data synced to Clareo: July 13, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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