The Relevance Between the microRNA-30e in Plasma and the Prognosis of Schizophrenia Patients

The plasma samples from 15 individuals with schizophrenia (with a diagnosis of ICD-10) and the equivalent healthy controls will be conducted with the quantification analysis of the microRNA-30e via real-time quantitative polymerase chain reaction(RT-PCR). The 15 patients enrolled should be the first-episode and have not been treated, or were drug free 3 months recently at least. This research measures the expression level of microRNA-30e in schizophrenia respectively before the beginning treatment with atypical psychotics or combined with MECT, after the 4-week treated , the 8-week treated compared with 15 healthy controls.