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Keep this study
Lead
University of Michigan
To investigate interictal opioid receptor (MOR) binding potential (BPND) changes in migraineurs as compared to age/gender-matched healthy controls. To demonstrate that frequency of the headache attacks and severity of cutaneous allodynia levels in migraineurs experienced over multiple attacks are correlated with levels of MOR BPND in specific brain regions. To investigate whether dysfunction of the pain regulatory endogenous opioid system of migraineurs is correlated with changes in the gray matter thickness in cortical areas associated with pain perception and modulation.
Age
18–45
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
Between 18-45 years of age
Between 1-14 migraine attacks per month or healthy
You may not be if
Cannot be taking daily migraine medication
Healthy subjects cannot be taking hormonal birth control pills or other medication
Cannot have chronic pain or a neurologic/psychiatric disorder such as: multiple sclerosis and bipolar disorder.
Clareo Health | Structural and Molecular Neuroplasticity in Migraine
