Affiliated Hospital to Academy of Military Medical Sciences
Age
18–75
Sex
FEMALE
Healthy volunteers
Not accepted
You may be eligible if
Female patients with advanced breast cancer who is confirmed historically.
New developing brain metastases (BM) is confirmed by gadolinium contrast-enhanced magnetic resonance imaging (MRI), with or without clinical symptoms and pathology, and without a history of BM treatment.
At least 2 BM lesions with the diameter of the largest lesion \< 40 mm is eligible. And the distance from the border of a mass to the hippocampal margin should be more than 15 mm.
The Eastern Cooperative Oncology Group (ECOG) is from 0 to 2, and the expected life expectancy is ≥3 months.
You may not be if
Concurrent chemoradiation.
Patient who had received cranial irradiation previously.
Patient who are enrolled in other clinical trial at the same time.
Patient who has severe co-morbidity or infection.
Clareo Health | Hippocampal-sparing Whole Brain Radiotherapy for Brain Metastases From Breast Cancer