Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Duke University
Age
35–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Documented resistant hypertension (RH). In the absence of a specific RH diagnosis, individuals being treated for two or more weeks with 3 antihypertensive medications of different classes, including a diuretic if tolerated, with clinic SBP ≥ 130 mm Hg or DBP ≥ 80 mm Hg, will be eligible. Individuals being treated with 4 or more antihypertensive medications, including a diuretic if tolerated, with SBP ≥ 120 or DBP ≥ 80 mm Hg will also be eligible.
Adherent to prescribed medications
Overweight (BMI ≥ 25 kg/m2)
Sedentary
Willing to be randomized to one of the 2 treatment groups and able to fully participate in intervention
Informed consent
You may not be if
Secondary HTN, non-adherence to anti-HTN medications
Severe CKD (eGFR \<40 ml/min/1.73m2)
Severe ischemic heart disease (CCS Class 3 or 4 angina or evidence of ischemia at \<85% heart rate reserve on treadmill testing)
Severe heart failure (NYHA association Class 3 or 4), high grade arrhythmias, severe valvular heart disease
Severe asthma or chronic obstructive lung disease
Diabetes requiring insulin
Musculoskeletal or neurologic problems that would preclude participation in aerobic exercise training
Major psychiatric disorder, a history of drug abuse, alcohol consumption \>14 drinks/week
Life-limiting comorbid medical condition such as cancer
Prior gastric bypass surgery
Currently pregnant
Cognitively impaired
Clareo Health | Neurocognition, Lifestyle Modification, and Treatment Resistant Hypertension
