A Study of Oxytocin for the Treatment of Social Impairment in Individuals With High Functioning Autism Spectrum Disorder

Inclusion Criteria

• •Males and females between 12 and 55 years of age.
• •Meets the DSM-5 diagnostic criteria for Autism Spectrum Disorder (ASD) as established by clinical diagnostic interview
• •At least moderate severity of ASD impairment as measured by a raw score of ≥85 on the SRS
• •Participants and their parent/guardian must be able to speak and understand English sufficiently to comprehend the nature of the study and to allow for the completion of all study procedures required per protocol.
• •Subjects and their parent/guardian must be considered reliable reporters. They must understand the nature of the study and must sign an IRB-approved informed consent form before initiation of any study procedures. Subjects and their parent/guardian must have a level of understanding sufficient to communicate with the investigator and study coordinator, and to cooperate with all tests and examinations required by the protocol.
• •Each subject and their parent/guardian must understand the nature of the study and provide written informed assent/consent.
• •Subjects with mood, anxiety, or disruptive behavior disorders will be allowed to participate in the study provided they do not meet any exclusionary criteria.
• •If the subject is sexually active, he/she must agree to use an acceptable form of birth control during the study. These include:
• •Abstinence (no sexual contact)
• •A barrier method (diaphragm plus spermicide or a condom plus spermicide) in addition to one of the following methods:
• •Consistent use of an approved birth control pill
• •Birth control patch
• •Injected contraceptives
• •Intrauterine device (IUD)