Age

18–75

Sex

ALL

Healthy volunteers

Not accepted

Radiologically proven colonic obstruction of the left colon/upper rectum presumed secondary to a carcinoma
Able to give written, informed consent
Primary tumor was resectable
ECOG score 0 or 1
Haemoglobin greater than 100 g/L after transfusion before chemotherapy,
White blood cells greater than 3.0×10⁹ /L
Platelets greater than 100×10⁹ / L;
Glomerular filtration rate greater than 50 mL per minute as calculated by the Wright or Cockroft formula
Bilirubin less than 1.5×Upper Limit of Normal(ULN)
ALT and AST less than 2.5×ULN

Distal rectal cancers(equal or less than 10cm from the anal verge)
Patients with signs of peritonitis and/or bowel perforation
Patients who did not give informed consent
Patients who were considered unfit for operative treatment or refuse surgery.
Patients with suspected or proven metastatic adenocarcinoma;
Patients with unresectable colorectal cancer, or planning for palliative treatment.

Neoadjuvant Chemotherapy Verse Surgery Alone After Stent Placement for Obstructive Colonic Cancer