Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Chugai Pharmaceutical
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
\- Patients with CKD and hyperphosphatemia must meet the following criteria for study entry:
Age ≥18 years
On thrice-weekly hemodialysis for at least 3 months prior to screening
Not having changed dialysis prescription within 4 weeks prior to screening for dialyzer, calcium concentration in dialysate, or dry weight more than 1 kg
Receiving stable doses of treatments affecting serum phosphorus for at least 4 weeks prior to screening and willing to discontinue these treatments
You may not be if
\- Patients with CKD and hyperphosphatemia who meet any of the following criteria will be excluded from study entry:
Uncontrolled diabetes and/or hypertension in the opinion of the investigators
Uncontrolled chronic constipation and/or diarrhea in the opinion of the investigators
Hospitalization for cardiac disease in previous 3 months
Evidence of acute or chronic hepatitis or known liver cirrhosis
Aspartate aminotransferase (AST) and/or alanine aminotransferase (ALT) \>2.5 x upper limit of normal (ULN)
