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Preoperative Breast Irradiation | Clinical Trials | Clareo Health

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TERMINATEDNANCT02941835

Preoperative Breast Irradiation

The PROBI is a phase I/II trial assessing the feasibility of preoperative whole breast irradiation in female patients with low to intermediate risk breast cancer, who undergo breast conserving therapy...

Lead sponsor: The Netherlands Cancer Institute•1 locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

The Netherlands Cancer Institute

Age

18 - 50 years

Sex

FEMALE

Healthy Volunteers

No

Inclusion Criteria

•Histologically proven invasive breast carcinoma
•cT1-2N0 breast cancer
•cM0
•female patients ≤ 50 years
•planned breast conserving surgery
•ability to undergo irradiation and surgery
•signed written informed consent

Exclusion Criteria

•prior surgery or radiotherapy for the protocol tumor (neoadjuvant chemotherapy or endocrine therapy is allowed)
•planned oncoplastic reduction mammoplasty
•cTis
•extensive calcifications on mammagram (Birads 3,4 or 5)
•cT3-4 and/or cN1-3 invasive carcinoma
•distant metastasis

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: October 22, 2019Terms

Trial snapshot

StatusTERMINATED

PhaseNA

Enrollment4

Start dateMar 2018

Last updatedOct 22, 2019

Condition

Locations shown

Netherlands Cancer Institute

Amsterdam

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: October 22, 2019Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions