Cognitive Biomarkers in Pediatric Brain Tumor Patients

Inclusion Criteria

• •Cohort 1 (30 patients will be enrolled to this cohort)
• •Between 4 and 18 years of age, inclusive
• •Newly diagnosed primary brain tumor of any location and any histology
• •Life expectancy of at least one year
• •Able to understand and willing to consent or assent to the research proposed, along with consent of legal guardian(s) if applicable
• •Between 4 and 18 years of age, inclusive
• •Previous diagnosis of a posterior fossa brain tumor; patients who are either undergoing active treatment for posterior fossa tumor or who have completed treatment will be eligible for study enrollment
• •Life expectancy of at least one year
• •Able to understand and willing to consent assent to the research proposed, along with consent of legal guardian(s) if applicable
• •Between 4 and 18 years of age, inclusive
• •Previous diagnosis of a posterior fossa brain tumor
• •Clinical diagnosis of post-operative posterior fossa syndrome
• •Inability to complete NIH Toolbox
• •Life expectancy of at least one year
• •Able to understand and willing to consent assent to the research proposed, along with consent of legal guardian(s) if applicable
• •Between 12-30 years of age, inclusive
• •Diagnosis of a brain tumor \>3 years prior to study enrollment
• •Life expectancy of at least one year
• •Able to understand and willing to consent assent to the research proposed, along with consent of legal guardian(s) if applicable
• •Patient must be able to complete a 1 hour MRI scan without sedation