Deep Brain Stimulation of the Sub-Thalamic Nucleus to Treat Severe and Treatment-resistant Cocaine Addiction.

Exclusion Criteria

• •a current opioid dependence will not be a criterion of non inclusion if the patient is undergoing substitution treatment (methadone or buprenorphine) and not injection of opiates for at least six months.
• •patient trust
• •pregnant, nursing or of childbearing potential without effective contraception
• •current use of the intravenous route for the administration of the drugs is the risk of infection
• •VIH infection or VHC unstabilized,
• •cardiovascular and / or brain state is not compatible with the surgery,
• •other disorder on Axis I not linked to cocaine use except:
• •* current or past dependence to nicotine,
• •* abuse or dependence on other psychoactive substances over a lifetime in remission for more than 6 months,
• •* current opioid dependence: if the patient is undergoing substitution treatment (methadone or buprenorphine) and not injection of opiates for at least 6 months,
• •* when other psychiatric disorders induced by substances.