Efficacy and Safety Trial With S 44819 After Recent Ischemic Cerebral Event

Exclusion Criteria

• •Any non-selection criteria, which could have occurred after the selection visit
• •Positive urinary or blood pregnancy test (for female patients of child bearing potential)
• •Any clinically significant findings from the local laboratory test likely to interfere with the ability to participate in the study and / or with the study outcome
• •Severe renal impairment detected in the local laboratory test
• •Severe hepatic impairment or liver enzymes abnormalities found in the local laboratory test
• •Stroke due to cerebral venous thrombosis
• •Brain MRI showing a severe microangiopathy
• •Brain imaging showing an acute haemorrhagic stroke or a symptomatic haemorrhagic transformation of the brain infarct
• •Qualifying ischemic cerebral event older than 192 hours at inclusion
• •Any clinically relevant abnormalities detected during the examinations likely to interfere with study procedures or study outcome,
• •Repeated prolongation of ECG QTcF
• •Patient or authorised representative refusing to attend study visits or to take part in the study