A Volumetric Analysis of Soft and Hard Tissue Healing for Ridge Preservation and Socket Seal After Tooth Extraction

Exclusion Criteria

• •Individuals who have a chronic disease with oral manifestations.
• •Individuals who exhibit gross oral pathology.
• •The use of either antibiotics or chronic use (more than 7 days) of NSAIDs within 1 month prior to screening examination.
• •Individuals that require antibiotic prophylaxis prior to dental treatment.
• •Chronic treatment (i.e. two weeks or more) with any medication known to affect periodontal status (e.g. phenytoin, calcium antagonists, cyclosporine, Coumadin) within 1 month prior to screening examination.
• •Uncontrolled diabetes mellitus (HbA1c \>7) within 3 months prior to screening examination.
• •Individual with uncontrolled parafunctional habits, such as clenching and bruxing on objects, that could adversely impact implant survival.
• •Individuals with a history of intravenous bisphosphonates.
• •Individuals with active infectious diseases such as hepatitis, HIV or tuberculosis.
• •Current cigarette smokers.
• •Individuals who are known to be pregnant, breastfeeding or planning to become pregnant within 6 months.
• •Individuals with blood disorders (hemophilia) and /or currently taking anticoagulant medications, such as heparin, warfarin, or clopidogrel.
• •Individuals receiving any therapy known to affect healing, such as high dose corticosteroids, radiation therapy or chemotherapy.
• •Individuals allergic to topical or local anesthesia.
• •Individuals who require maxillary sinus augmentation prior to dental implant therapy.
• •Individuals with dehisced, fenestrated, or fractured labial/buccal alveolar bone plate determined after baseline CBCT or after tooth extraction where more than 50% of the buccal bone height is not present. In this case, if the surgeon determines that guided bone regeneration (bone graft and membrane) is needed to repair the defect, it will be done at no cost to the subject, but the subject will be excluded from the study protocol.