Everolimus Modulation of Anti-tumor T CD4 Immune Responses

Exclusion Criteria

• •Patients under chronic treatment with systemic corticoids or other immunosuppressive drugs (prednisone or prednisolone ≤ 10 mg/day is allowed)
• •History of immune deficiency
• •Hypersensitivity against rapamycin and derived
• •Prior history of other malignancy except for: basal cell carcinoma of the skin, cervical intra-epithelial neoplasia and other cancer curatively treated with no evidence of disease for at least 5 years
• •Active autoimmune diseases, HIV, hepatitis C or B virus
• •Patients with any medical or psychiatric condition or disease,
• •Patients under guardianship, curatorship or under the protection of justice.