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COMPLETEDPhase 2NCT02813551

ToRsemide for pOstpartum HYpertension

Currently there is no intervention to prevent persistent postpartum hypertension in preeclamptic women. Physiologically, the use of a pharmacokinetically predictable loop-diuretic is a reasonable inte...

Lead sponsor: The University of Texas Health Science Center, Houston•1 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

The University of Texas Health Science Center, Houston

Age

18 - No limit years

Sex

FEMALE

Healthy Volunteers

Yes

Inclusion Criteria

•Postpartum women at ≥ 18 years of age
•Antepartum/intrapartum or within 24 hours postpartum diagnosis of either:
•Preeclampsia
•Preeclampsia with severe features
•Preeclampsia superimposed to chronic hypertension

Exclusion Criteria

•Chronic hypertension without superimposed preeclampsia
•Gestational hypertension
•Urine output \< 30 cc/h at time of randomization
•Heart failure or pulmonary edema
•Hypersensitivity to Torsemide or sulfonylureas
•Hypokalemia (serum potassium \< 3 mEq/L)
•Preexisting diuretic use within 24 hours prior to randomization

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: April 10, 2019Terms

Trial snapshot

StatusCOMPLETED

PhasePHASE2

Enrollment118

Start dateAug 2016

Last updatedApr 10, 2019

Condition

Locations shown

The University of Texas Health Science Center

Houston, Texas

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: April 10, 2019Data synced to Clareo: July 13, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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