FiO2 Closed Loop Control Ventilation

Exclusion Criteria

• •Age under 18 or over 65
• •Isolated or severe head injury (Glasgow Coma Scale = 6 or less) with expected survival less than 24 hours
• •Brain death
• •Anticipated survival less than 48 hours
• •Pregnant female
• •Patient in whom a pulse oximeter cannot detect a reliable signal due to hypotension, hypothermia, or other injury
• •Known carbon monoxide poisoning
• •Uncontrolled diabetic
• •Patient who is unable to maintain SpO2 level of 88% at an FiO2 of 100% due to their medical condition. (NOTE: Being in the trial would impose no additional risk to a patient who presents with this condition however, data from a patient presenting with this pathophysiology would not provide insight into the performance of the controller as it would simply maintain that patient on an FiO2 of 100%.)
• •Patient with chronic hypercarbia.
• •Patient where a physician believes that FiO2 PCLC could be detrimental to the management of the patient.
• •Prisoner
• •SpO2 to SaO2 difference \>4%
• •Patient with core temperature \<35 C