Detection of Cav1 Calcium Channels in Inflammatory Cells of Asthmatic Children

Exclusion Criteria

• •For both arms:
• •Chronic respiratory pathology : known occlusive or restrictive respiratory syndrome like interstitial lung disease, neuromuscular disease, mucoviscidoses, respiratory tract abnormalities with cough, dyspnea or digital hippocratism.
• •History of pulmonary or nose and throat infectious disease during last 4 months
• •Parasitic disease non treated during last 3 months
• •Dyspnea during the inclusion
• •Systemic corticotherapy during the last 3 months before inclusion
• •Immunosuppressive therapy during the last 3 months before inclusion
• •Diabeta
• •Disease causing immune disorder
• •Infection during inclusion
• •Participation to another study witch implies medical treatment during last 3 months before inclusion
• •For asthmatic children arm :
• •Chronic pulmonary pathology (excluding asthma)
• •Asthma exacerbation during inclusion
• •VEMS \< 70% of normal range or VEMS \< 70% of normal range after inhalation of serum (despite salbutamol administration)
• •Patient unable to complete pulmonary function testing