Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Tricida, Inc.
Age
18–80
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Estimated glomerular filtration rate (eGFR) of 20 to \<60 mL/min/1.73m2
Serum bicarbonate level of 12 to 20 mEq/L
You may not be if
Any level of low serum bicarbonate that, in the opinion of the Investigator, requires emergency intervention.
Severe comorbid conditions other than chronic kidney disease.
Chronic obstructive pulmonary disease.
Anticipated changes in doses of any of the following drugs or drug classes: diuretics, non-ophthalmic carbonic anhydrase inhibitors, oral diabetes drugs, antihypertensive drugs, antacids, H2-blockers, or proton pump inhibitors.
Excluded drugs or drug classes: insulin, non-daily or "as needed" diuretics, herbal products, dietary supplements, multivitamins, naturopathic remedies, sodium bicarbonate, potassium citrate, sodium citrate or other alkali therapy, non-steroidal anti-inflammatory drugs (NSAIDs), fiber supplements, laxatives, calcium and magnesium supplements, or electrolyte binders and other binder drugs.
