Institutul Regional de Gastroenterologie & Hepatologie Prof. dr. Octavian Fodor
With
Prof. Dr. I. Chiricuta Institute of Oncology
Main goals
1. Comparative evaluation of the incidence of recurrences after TIVA vs sevoflurane anesthesia
2. Evaluation of the effect of lidocaine infusion associated with TIVA/sevoflurane on the incidence of chronic pain and of cancer recurrences and survival.
Secondary objectives
1. Evaluation of the influence of lidocaine on postoperative outcome in patients with colorectal cancer
2. Evaluation of the influence of lidocaine on postoperative inflammatory response
3. Evaluation of the influence of lidocaine on the incidence and severity of postoperative pain and outcome in patients with colorectal cancer
Age
18–80
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Elective surgery
You may not be if
• persistent chronic pain
* chronic medication that may interfere with pain: antiepileptics, NSAID, corticoids
* Contraindications for any of the study medications
