Evaluation of the Improvement of Quality of Life of Patients Suffering From Hailey Hailey or Darier Disease After Injections of Botulism Toxin Into Large Folds.

Exclusion Criteria

• •Hypersensibility to toxin or excipients
• •Myastheny
• •Deglutition's problems
• •Past medical history of dysphagia or aspiration pneumonia
• •Pregnancy (positive B-HCG test performed a maxima 72h before) or breastfeeding
• •Mental , physical incapacity to fill in the questionnaires
• •Guardianship patients
• •Skin infections at the inclusion visit
• •Application in the last 7 days at the site of injection of local treatments (apart emollients or antiseptics) or injections of botulism toxin or dynamic phototherapy or laser in the last 6 months.
• •Systemic treatment with aminosides in the last 15 days
• •Inclusion in another study in the last 2 months.