A Study of Oral Hymecromone and Hyaluronan Synthesis

Inclusion Criteria

• •Male or female 18-65 years of age
• •Healthy adult with no active medical problems or significant chronic diseases as determined by the study doctor based on history, physical exam
• •BMI between 18.5 - 30 kg/m2
• •Taking no medications for at least 1 week before and during study enrollment, including drugs of abuse, prescription or OTC medications
• •Male subjects who are heterosexually active must use an acceptable method of contraception (abstinence, condom with or without spermicidal agent, or partner contraceptive use as described in requirements for female subjects) to avoid pregnancy in their partner for the entire study period
• •Female subjects who are heterosexually active must use an acceptable method of contraception: condoms (male or female) with or without a spermicidal agent, diaphragm or cervical cap with spermicide, IUD, or Hormone-based contraceptive
• •Be able to provide written informed consent and comply with requirements of the study
• •Abstinence from alcoholic beverages, caffeinated beverages and orange juice from 3pm the night before a study day until completion of that study day
• •Be able to read, speak and understand English
• •Able and willing to understand the study, adhere to all study procedures, and provide written informed consent