The Success of Opening Single CTO Lesions to Improve Myocardial Viability Study (SOS-comedy)

Exclusion Criteria

• •Acute Q-wave myocardial infarction during the latest 3 months
• •Revascularization in the non-culprit artery during the latest one month
• •Unsuitable for PCI
• •Unable to tolerate dual antiplatelet treatment (DAPT)
• •Severe abnormal hematopoietic system, such as platelet count of \< 100×109/L or \> 700×109/L and white blood cell count of \< 3×109/L
• •Active bleeding or bleeding tendency
• •Severe coexisting conditions, such as severe renal insufficiency (GFR \< 60 ml/min•1.73m2), severe hepatic dysfunction \[elevated ALT (glutamic-pyruvic transaminase) or AST (glutamic-oxal acetic transaminase) level by more than three-fold of the normal limitation\], acute or chronic heart failure (NYHA III-IV), acute infectious diseases, immune disorders, malignancy, etc.
• •Life expectancy \< 12 months
• •Pregnancy or planning pregnancy
• •Drug allergies or contraindications to aspirin, clopidogrel, ticagrelor, statins, contract, anticoagulant, stent, etc.
• •Participation or planning to participate in another clinical trial during the same period
• •Refusal to comply with the study protocol