Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may not be if
Intended to receive palliative radiotherapy to the thorax, to a dose of 30Gy in 10 fractions or 20Gy in 5 fractions. In either treatment arm at least 5cm of the esophagus should be in the intended treatment field.
Willingness and ability to provide informed consent
Eastern Cooperative Oncology Group (ECOG) performance status 0-3
Age 18 years or older
Prior or planned systemic therapy (chemotherapy, immunotherapy, targeted agents) is permissible at the discretion of the treating medical oncologist, provided that no systemic treatment is given within 2 weeks prior to RT, concurrent with RT or within a 2-week period post RT.
Concurrent palliative RT to other metastatic sites is permissible
Life expectancy \> 3 months
Prior thoracic RT
Serious medical comorbidities precluding RT
Pregnant or lactating women
Inability to attend the full course of RT or planned follow-up visits
Planned concurrent palliative RT to the stomach and/or liver
Congenital abnormalities of the esophagus or severe disorders of the esophagus (e.g. achalasia)
Clareo Health | A Randomized Phase III Study of Palliative Radiation of Advanced Central Tumors With Intentional Avoidance of the Esophagus
