May Metformin be Used in Renal Failure?

Inclusion Criteria

• •Diabetic patients not treated with metformin, no treatment diabetic or have been treated but poorly balanced (HbA1c\> 7%) and an applicant building with metformin; at any stage renal stable (stages 1-5 according to the classification MDRD)
• •Patients aged 18 to 80 years;
• •Patients with an assessment of renal function dating back more than 3 months;
• •Patients whose renal function is stable, on the criterion of the absence of fluctuation over 30% of renal function of creatinine clearance in the last three months, a reference to renal function at least 3 months from the balance sheet inclusion is necessary.