Contrast-Enhanced Ultrasound in Predicting Treatment Response in Patients With Kidney Cancer Undergoing Cryosurgery

Exclusion Criteria

• •Females who are pregnant or nursing
• •Patients who are medically unstable, patients who are seriously or terminally ill, and patients whose clinical course is unpredictable; for example:
• •* Patients on life support or in a critical care unit
• •* Patients with unstable occlusive disease (eg, crescendo angina)
• •* Patients with clinically unstable cardiac arrhythmias, such as recurrent ventricular tachycardia
• •* Patients with uncontrolled congestive heart failure (New York Heart Association \[NYHA\] class IV)
• •Patients with recent cerebral hemorrhage
• •Patients with known sensitivities to albumin, blood, or blood products
• •Patients who have undergone surgery within 24 hours prior to the study sonographic examination
• •Patients with known hypersensitivity to perflutren
• •Patients who have received any contrast medium (X-ray, MRI, CT, or ultrasound \[US\]) in the 24 hours prior to the research US exam
• •Patients with cardiac shunts
• •Patients with congenital heart defects
• •Patients with severe emphysema, pulmonary vasculitis, or a history of pulmonary emboli
• •Patients with respiratory distress syndrome
• •Patients with renal insufficiency such that they can not get intravenous contrast as part of screening or follow-up