Assessing Covert Consciousness in Unresponsive Patients

Exclusion Criteria

• •• Elevated intracranial pressure (ICP)
• •* Hepatic or renal failure
• •* Hemodynamic instability
• •* Active vasopressor therapy
• •* Previous open-head injury
• •* Previous intracranial pathology requiring neurosurgical interventions in the past 72 hours
• •* Anticipated ICU stay \< 24 hours
• •* Documented allergy to propofol
• •* Pregnancy
• •* BMI \> 35 kg/m2
• •* Anyone who is deemed medically unsuitable for this study by the attending intensivist
• •* Patients who are already in a medically-induced coma for intracranial hypertension or status epilepticus