Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
With
Sun Yat-sen University
Huiping Li,M.D., Ph.D.,Peking University Cancer Hospital
Age
18–any
Sex
FEMALE
Healthy volunteers
Not accepted
You may be eligible if
1. The patients signed the written informed consent
2. female patient who is ≥ 18yrs,
3. HER2 positive: immunohistochemistry (+++) or FISH (+)
4. stage IV
5. the patients have no history of chemotherapy ,hormone therapy,radiotherapy or surgery after diagnosis of breast cancer
6. the result of patients' blood tests are as follow: WBC≥3.0×109/L; Plt≥100×109/L;AST/SGOT or ALT/AGPT≤tripple of normal upper limit; Creatinine\<double of the normal upper limit
7. ECOG scores are 0 or 1 .
8. The patient is able to take oral pills
You may not be if
1. The patient was never exposed to herceptin.
2. The patient suffered from other non-breast malignancy in the last 5 years, except for cervical carcinoma in situ, radical basal cell carcinoma or squamous cell carcinoma.
3. The life expectancy is less than 3 months.
4. Severe hepatic function disorder, Child Pugh grade C.
5. Severe cardiac function disorder, cardiac function is more than grade III;
6. Prolonged QT interval;
7. Arrhythmia or taking anti-arrhythmia drugs;
8. Pregnant or breast feeding female.
Clareo Health | microRNA of Human Epidermal Growth Factor Receptor 2 （HER2）Positive Patient Treated With Herceptin
